https://jbeb.avestia.com/2023/005.html

Abstract: Computed Tomography-based Finite Element Model (CT-FEM) is a powerful tool that enables the collaboration of clinicians and engineers in biomechanics. It allows accurate and efficient simulations to improve understanding of complex biological problems. Despite its potential benefits, computational biomechanics using CT-FEM faces several challenges when dealing with complex geometries. To address this challenge, an advanced methodology is here developed by using four different software simultaneously. The software can work together and supply user interaction to complete the segmentation, surface reduction, surface mesh generation, and acoustic analysis. One of the most challenging geometries, the human thorax with multiple internal organs, was chosen to test the methodology. The approach has been validated against two different and independent experimental studies available in the literature. It could be used to offer insights into the effects on the multiple internal organs in many clinical and therapeutic studies. This specific approach allows researchers to explore complex interactions happening inside the human body, resulting in major advancements in comprehending physiological and pathological procedures.

Keywords: CT-FEM, Geometry repairment, Numerical modelling, Airway clearance treatment

Date Published: October 12, 2023
DOI: 10.11159/jbeb.2023.005

View Article